Filtration Efficiency
Filtration Efficiency is usually stated in terms of the percentage of particles of a certain size that would be stopped and retained by a filter medium.
What Is The Filtration Retention of A Laboratory Syringe Filter?
The retention rate is an important parameter for the Laboratory Syringe Filter. When using a filter for filtration, undesired components are often captured by the filter. The retention rate represents the ability of the membrane to either prevent certain components from passing through or retain a specific component in the liquid. Due to different calculation formulas, various numerical values can be obtained.
The commonly used calculation formula is
In the equation:
R—retention rate;
CP—permeate concentration;
CF—feed concentration;
CP and CF can be expressed in any concentration unit, but both should have the same unit.
In order to investigate the retention rate of different material filter membranes, this experiment determined the retention rate of the filter membrane by detecting the concentration of 300nm standard microspheres before and after filtration.
Experimental Instruments and Consumables
Instrument:Nanocoulter Coulter Counter
laboratory Syringe Filters:0.22μm PVDF, 0.22μm PES, 0.22μm MCE
What Happens After A Solution Filtered?
300 nm Standard Microspheres before filtered
300 nm Standard Microspheres before filtered
The particle size range of the 300nm standard microspheres before filtration is between 150 to 450nm, with a concentration of 9.02E+11 Particles/mL. After filtration, the particle size distribution of the sample is in the range of 150 to 350nm, and the concentration is reduced to only 1.28E+10 Particles/mL. By comparing the concentration data before and after filtration, it is determined that the retention rate of the 0.22μm membrane for filtering 300nm standard microspheres reaches 98.58%.
The experiment further examined the permeate concentration after filtration by a 0.22μm filter for four different-sized latex microsphere samples and one exosome sample, and the data for retention rates are summarized as follows:
How Filtration Retention Varies from Different Material Filter Membranes
From the data graph, it can be observed that there are significant differences in the filtration performance of filters made of different materials. For latex microspheres, three filters of different materials exhibit a consistent trend: as the particle size of the microspheres increases, the corresponding retention rate also increases.