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0.22μm Syringe Filter VS. 0.45 μm Syringe Filter: How To Make A Choice

0.22μm Syringe Filter: With Sterilizing-grade Membrane Inside

 

With a higher filtration precision, it can filter out microorganisms, cells, etc., with a diameter larger than 0.22 micrometers. It is generally used to remove extremely fine particles in samples or mobile phases, meeting the requirements of sterilization at 99.99% according to GMP or pharmacopeia standards. Therefore, it is called a sterile filtration membrane and is commonly used in the pharmaceutical, medical, and food industries. Compared to membranes with larger pore sizes, the 0.22μm membrane has higher resistance during filtration, requiring higher pressure to allow the liquid to pass through the membrane pores.

 

Remove Bacteria by pvdf filtration
Remove Bacteria by pvdf filtration

Escherichia coli bacterial solution Before Filtered by 0.22 μm PVDF Syringe filter 

Escherichia coli bacterial solution After Filtered by 0.22 μm PVDF Syringe filter

0.45μm Syringe Filter: Reducing Microbial Load


It can filter out most bacterial microorganisms and is suitable for filtering routine samples and mobile phases to meet general chromatographic requirements. It reduces microbial load, has a high flux, and requires relatively low pressure.

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